Brain of Psychopaths: differences in function and structure

Making up approximately 1% of the U.S population and up to 20% of the country’s prison population, psychopath and criminals with psychopathic traits is a major focus in both the legal system and neuroscience research. Many studies have already been conducted on the brains of psychopaths in hopes of elucidating clues about the causes of their antisocial behaviors. According to one review by Blair, it has been previously revealed that psychopaths exhibit increased levels of proactive and reactive aggression. Furthermore, through fMRI studies it has been found that people with psychopathic traits often have reduced amygdala and orbito-frontal cortex activities. While it has been shown that the activities in these brain regions are reduced in psychopaths, the actual physical difference that causes these reductions has yet to be presented.

However, recently a new study conducted by Newman et al reveals decreased physical connections between the amygdala and the ventromedial prefrontal cortex (vmPFC). Amygdala is critical in mediating fear and anxiety while the vmPFC is responsible for “sentiments such as empathy and guilt.” Combined, the lessened connection leads to a lower activity by these brain regions that may explain the antisocial impulses displayed by psychopaths. The researchers of this study utilized a diffusion tension imaging device (DTI) and compared results between 20 psychopathic prisoners and 20 non-psychopathic prisoners that committed similar crimes. Results revealed a “reduction in structural integrity of white matter fibers” that connects the two brain regions. Additionally, an fMRI scan was performed. Similar to previous findings, researchers found less coordinated activities. This study is perhaps the first to present both structural and functional differences in the brains of a psychopath. According to Dr. Koenigs of the research team, these results indicate that there is “a specific brain abnormality that is associated with criminal psychopathy.”

With these findings, the researchers at University of Wisconsin-Madison hope to shed more light on the source of the dysfunction and future strategies in treating psychopathy. Furthermore, the researchers discuss the legal implications of their findings. They question whether the legal system can hold psychopaths as accountable as someone that does not have a brain abnormality. I believe while the legal system should react to psychopaths differently, they should not be forgiven solely base off of brain differences. It is still necessary to take them off the streets if they committed a serious crime. However, perhaps the more appropriate long term response is to employ rehabilitation and treatments rather than incarcerations and punishments.

Brains scans measure racial bias

http://www.yaledailynews.com/news/2011/nov/14/brain-scans-measure-racial-bias/

It is common knowledge that a degree of racial bias tends to color juries’ decisions. As much as jurors try (or don’t try) to remain unbiased in their verdicts, all convicted individuals deserve an unbiased trial. In her article “Brain scans measure racial bias,” Jacqueline Sahlberg discusses Yale Law School’s novel use of brains scans to predict jurors’ racial bias better than previous testing methods. This new method of testing holds implications in the development and growth of neurolaw because brain scans can be employed to ensure a fairer trial.

Currently, the implicit association test is used as the standard of measuring racial bias of individuals, and predictions are made based on the reaction time of individuals asked to match positive or negatives adjectives with peoples of different race. A modest correlation exists when using this test, but the new brain scans have been suggested as the next step in decreasing bias in the courtroom. The brain scans use fMRI to predict the racial bias’ of potential jurors, a fairly developed technology that measures changes in brain blood flow to indicate which portions of the brain are active when specific stimulations are administered. In the past, fMRIs tended to emphasize a single region’s response to stimuli instead of looking at the entire brain. When Yale observed the holistic changes in brain blood flow, fMRI had a higher correlation with the predicted verdict than did the IAT when theoretical questions regarding monetary compensation in employment discrimination cases were posed.

These results are significant in that they validate the use of neurolaw to correct and create an overall better court system, easing the minds of wary critics. However, the fMRIs a long ways from being the new standard. The high cost of $1000 per participant is a large barrier for daily use, and until these costs are ameliorated, these scans are not a viable option for juror bias testing. The article proves the efficacy of employing neuroscience to create a fairer and more efficient justice system.

http://www.yaledailynews.com/news/2011/nov/14/brain-scans-measure-racial-bias/

The PTSD Brain

The psychological and neurological gap in the spectrum of Post-Traumatic Stress Disorder (PTSD) is finally bridged. Using Magnetoencephalography (MEG), a noninvasive technique that measures the magnetic fields in the brain, researchers at the University of Minnesota Medical School were able to identify particular brain activities that significantly correlate with PTSD. They found increased activities in the temporal and parieto-occipital right hemispheric areas of the brain among individuals with PTSD. Using the new finding, the researchers were able to objectively diagnose PTSD with 96 percent accuracy, while classifying healthy individuals with 95 percent accuracy in a study trial involving 80 subjects with confirmed PTSD, 18 subjects in PTSD remission, and 284 healthy subjects. From the perspective of the legal system, I believe the objectivity and the high accuracy would be invaluable contributors in determining the mental state and thus the criminal intent of a defendant in trial.

Taking a step back, how pertinent is PTSD to criminal activities? Research shows that higher rates of aggressive behavior are seen in those with PTSD, compared to those without PTSD. One explanation is that the insecurities caused by the traumatic experiences may manifest into heightened irritability, hyper-vigilance, exaggerated startle response and distress. As a result, individuals with PTSD can experience impaired cognitive abilities. They could easily feel threatened in many situations or even have flashback in which they believe they are in the traumatic incident again, both of which would cause the PTSD sufferers to act impulsively in order to protect themselves. The augmented aggression in individuals with PTSD therefore could translate into criminal behaviors without any criminal intent.

Moreover, the PTSD symptoms described do not necessarily need an external stimulator to occur. In the same research study using MEG at the University of Minnesota, the brains of PTSD individuals remained hyperactive even in the “task-free state” without any stimulating factors. In another words, PTSD sufferers can relive terrifying memories at any moment regardless of what they are doing.” This finding is critical for judging the mental state of a defendant as well as for future preventive measures. This elucidates the understanding that a PTSD individual could very well be in a “mentally diseased” state at the time of the crime albeit the lack of provocations. Also, as the legal system works toward a rehabilitative treatment for the mentally ill criminals, this knowledge should be taken into consideration. The spontaneous PTSD episodes would complicate any preventive or rehabilitative measures using strictly environmental constructions since the offset of a PTSD episode may not depend on the environment at all.

Overall, I believe the MEG study provides a profound insight into how discoveries and technologies in neuroscience could offer new approaches in the legal system. More research studies on particularly criminals with PTSD should be worked on before the implementations of MEG brain scans in courts should be considered. Nonetheless, I believe that MEG brain scans would be a promising tool for diagnosing and determining the severity of PTSD in a defendant, especially given the objectivity and the accuracy of the information now.

Sources:

New Findings on PTSD and Brain Activity < http://www.discoverpsychology.com/new-findings-on-ptsd-and-brain-activity.html>

U scientists find definitive indicator of PTSD < http://www.mndaily.com/2010/11/01/u-scientists-find-definitive-indicator-ptsd>

Criminal Behavior and PTSD: An Analysis < http://www.ptsd.va.gov/professional/pages/criminal-behavior-ptsd.asp>